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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TCF3 All Species: 10.3
Human Site: Y150 Identified Species: 28.33
UniProt: P15923 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15923 NP_001129611.1 654 67600 Y150 M K G T S Q Y Y P S Y S G S S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001084466 821 88777 Q300 K P G S Q Y Y Q Y S S N N P R
Dog Lupus familis XP_542197 632 64907 Y149 G T K G G S Q Y Y S Y P G H P
Cat Felis silvestris
Mouse Mus musculus P15806 651 67682 Y151 I K S S S Q Y Y P S F P S N P
Rat Rattus norvegicus P21677 649 67636 Y151 V K S S S Q Y Y T S F P S N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520330 471 50186 P22 A G Y A S S K P P S T V Y P A
Chicken Gallus gallus P30985 657 70524 S146 P S S V Y R P S P N S D D F N
Frog Xenopus laevis Q01978 658 70072 Y153 A G K A G S Q Y Y T Y P N N S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P11420 710 73846 N185 Q Q A P V N V N V N P P A V F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 43.3 81.6 N.A. 83.1 82.1 N.A. 47.2 47 64.4 N.A. N.A. 23.6 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 54.9 85.4 N.A. 88.8 88.3 N.A. 55.2 62.7 75.6 N.A. N.A. 36.3 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 20 26.6 N.A. 46.6 40 N.A. 20 6.6 20 N.A. N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 33.3 26.6 N.A. 73.3 66.6 N.A. 26.6 26.6 33.3 N.A. N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 0 12 23 0 0 0 0 0 0 0 0 12 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 12 12 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 23 0 0 12 12 % F
% Gly: 12 23 23 12 23 0 0 0 0 0 0 0 23 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % H
% Ile: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 34 23 0 0 0 12 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 0 12 0 23 0 12 23 34 12 % N
% Pro: 12 12 0 12 0 0 12 12 45 0 12 56 0 23 34 % P
% Gln: 12 12 0 0 12 34 23 12 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 12 % R
% Ser: 0 12 34 34 45 34 0 12 0 67 23 12 23 12 23 % S
% Thr: 0 12 0 12 0 0 0 0 12 12 12 0 0 0 0 % T
% Val: 12 0 0 12 12 0 12 0 12 0 0 12 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 12 12 45 56 34 0 34 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _